"I'm not particularly interested in running for president." Former Tennessee Senator Fred Thompson in response to a question by an Iowa voter about criticism that he's been a lackluster campaigner since becoming a presidential candidate.

"I did not say that it should be done, but I certainly recognize why Governor Spitzer is trying to do it." – Sen. Hillary Clinton during a presidential debate on whether New York Gov. Spitzer's proposal to issue driver's licenses to illegal aliens was a good idea. Coming within minutes of a statement apparently supporting Spitzer's proposal, the comment was widely seen as evidence of Clinton trying to have it both ways and preceded a sharp decline in her standing in the polls.

"I don't recall." – Former Attorney General Alberto Gonzales.

"In Iran, we don't have homosexuals like in your country. We don't have that in our country." – Iranian President Ahmadinejad at Columbia University in response to a question about mistreatment of women and homosexuals in Iran.

"That’s some nappy-headed hos there." – Radio/TV talk show host Don Imus (the comment that lead to him being fired)

"My goal is to goad people into saying something that ruins their life." – Don Imus

Classic Miss Quotes:

"Mission accomplished." – George Bush

"I actually did vote for the $87 billion before I voted against it." – Sen. John Kerry

"I did not have sex with that woman." – Bill Clinton

"I am not a crook." – Richard Nixon